A newsletter for those involved in clinical trials. Published 20 times a year by Canary Ltd

Investigational product

The following articles on this topic have been published in CRAdvisor (CRA) – the year, issue number and starting page number for each are listed below:

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2007  
CRA 2007; 183:4 FDA proposes new rule for experimental drugs.
CRA 2007; 190:4 How to avoid inspection problems with the product specification file.
CRA 2007; 191:4 EC guidance on IMPs and non-IMPs.
CRA 2007; 195:7 Biological samples and trials in Russia.
   
2006  
CRA 2006; 180:2 QP release of IMP documentation at study site.
CRA 2006; 182:7 IMP or non-IMP?
   
2005  
CRA 2005; 152:8 New guidance for trial pharmacists.
CRA 2005; 176:11 QP certificate may be required at study site.
   
2004  
CRA 2004; 130:7 Guidance on transitional arrangements for QPs.
CRA 2004; 131:2 Highlights of changes and new material in the April 2004 revision of the Detailed Guidances.
   
2002  
CRA 2002; 81:2 New draft of Annex 13 now available.
CRA 2002; 83:6 Mutual Recognition Agreement closer for GMP.
CRA 2002; 93:2 Requirements for export of investigational drugs to change.
   
2001  
CRA 2001; 72:4 Trade mark problem threatens quality of EU products.
CRA 2001; 74:6 Drug makers receive BSE warning.
CRA 2001; 75:5 EU GCP Directive and IMPs.
   
2000  
CRA 2000; 40:1 Do monitors break the law by collecting trial materials from the site?
CRA 2000; 43:4 Clinical supplies or clinical surprise!
CRA 2000; 44:5 Clinical supplies of clinical surprise – part 2.
CRA 2000; 46:6 EU Pharmaceutical and Cosmetics Unit.
   
1999  
CRA 1999; 19:3 NLN’s correct use of medicines.
CRA 1999; 22:4 ‘Just-in-time’ shipping.
CRA 1999; 22:4 Import of trial drugs made easier in Russia.
CRA 1999; 24:3 All investigational products must comply with GMP.
CRA 1999; 24:4 Investigational product for trial purposes cannot be sold.
CRA 1999; 24:5 Qualified person required.
CRA 1999; 29:6 Better training on product accountability.
CRA 1999; 36:6 “Deadly pills in UK.”
   
1998  
CRA 1998; 6:1 Details of destruction of trial supplies needed.
CRA 1998; 9:4 Resistance against ruling on destruction of trial supplies.
CRA 1998; 12:5 BSE from medicines?
CRA 1998; 12:6 TSE Certificates for comparator drugs bought in the USA.
CRA 1998; 13:2 Understanding expiry dates.
CRA 1998; 13:5 Trial products and labelling.
CRA 1998; 14:4 A practical approach to the retention of trial materials.
CRA 1998; 15:1 Annex 13 of the Guide to Good Manufacturing Practice.
CRA 1998; 16:3 FDA working party on pregnancy labelling.

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