A newsletter for those involved in clinical trials. Published 20 times a year by Canary Ltd

Ethical issues

The following articles on this topic have been published in CRAdvisor (CRA) – the year, issue number and starting page number for each are listed below:

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2006  
CRA 2006; 170:7 Best practice in research conduct.
CRA 2006; 171:7 Initiative to promote best practice in UK research.
CRA 2006; 182:2 Revised ethics guidance for trials in children.
CRA 2006; 182:11 Consumers for Ethics in Research to disband this month.
CRA 2006; 182:11 End-of-life care.
   
2005  
CRA 2005; 147:6 NIH announces ethics reform.
CRA 2005; 154:4 2001/20/EC: procedures in Belgium.
CRA 2005; 157:6 US National Institutes of Health issues final ethics rule.
   
2003  
CRA 2003: 102:1 WHO updates international ethical guidelines for clinical studies.
CRA 2003; 103:3 Ethics and research in developing countries.
CRA 2003; 120:4 WHO's contributions to research ethics.
   
2002  
CRA 2002; 82:7 UK national anti-fraud body proposed.
CRA 2002; 84:2 WHO expresses concerns on publication practices.
CRA 2002; 89:1 Guidance for genetic investigation.
CRA 2002; 90:6 New draft of CIOMS bioethics guidelines expected soon.
   
2001  
CRA 2001; 61:5 Ethical considerations in HIV preventative research.
CRA 2001; 63:1 Horrific extent of organ research revealed.
CRA 2001; 63:4 Patient Protection Procedures to be revised.
CRA 2001; 64:4 International trials - are they performed ethically?
CRA 2001; 66:1 Australians used as guinea-pigs for global drug market".
CRA 2001; 67:3 Early termination of studies may harm subjects.
CRA 2001; 71:6 CIOMS issues new ethics guidance.
CRA 2001; 74:6 Journals to demand author's independence.
CRA 2001; 77:6 Pharmaceutical funding for AMA.
CRA 2001; 78:6 Research fraud observed by consultants.
CRA 2001; 80:8 National award program to promote subject protection.
   
2000  
CRA 2000; 41:5 US guidance for research in mental disorders.
CRA 2000; 42:5 Stopping clinical trials is unethical.
CRA 2000; 42:6 Post-patient trial meeting?
CRA 2000; 44:3 Do volunteers know the consequences of secret trials?
CRA 2000; 44:4 Survey of ethical misconduct perceptions.
CRA 2000; 47:4 “Human beings as guinea pigs.”
CRA 2000; 48:1 UK Government to ‘save’ clinical trials.
CRA 2000; 50:4 Ethics Committees and protocol amendments.  
CRA 2000; 55:3 Financial disclosure and conflicts of interest.
CRA 2000; 56:3 Use of placebo still major cause of ethical unrest. 
CRA 2000; 56:4 Inappropriate patient recruitment procedures.
CRA 2000; 59:1 Investigator need may jeopardise trial subject safety.
   
1999  
CRA 1999; 20:6 Will Ethics Committees cap the recruitment time?
CRA 1999; 23:4 When is a protocol amendment an administrative change?
CRA 1999; 24:6 Financial arrangement with investigator not subject to Ethics Committee scrutiny.
CRA 1999; 25:1 Why not pay patients who take part in trials?
CRA 1999; 32:5 Making the healthy sick for trials.
   
1998  
CRA 1998; 3:1 Justifying the use of placebo: regulations versus ethics.
CRA 1998; 3:3 Ethical principles and the use of placebo.
CRA 1998; 10:1 All risks or just some risks?
CRA 1998; 18:5 When is a protocol amendment an administrative change?

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