A newsletter for those involved in clinical trials. Published 20 times a year by Canary Ltd

Detailed Guidances

The following articles on this topic have been published in CRAdvisor (CRA) – the year, issue number and starting page number for each are listed below:

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2006  
CRA 2006; 169:2 EC issues revised Detailed Guidance on ethics committee applications.
CRA 2006; 170:1 Updated Detailed Guidance published on the collection and reporting of adverse reactions.
CRA 2006; 170:1 European Commission, not EMEA.
CRA 2006; 171:2 Revised Detailed Guidance on adverse reactions.
   
2004  
CRA 2004; 131:1 Revised Detailed Guidances issued to support implementation of Directive 2001/20/EC.
CRA 2004; 131:2 Highlights of changes and new material in the April 2004 revision of the Detailed Guidances.
CRA 2004; 137:1 The impact of EU Directive 2001/20/EC on commercial sponsors.
   
2003  
CRA 2003; 102:1 Detailed Guidances: no news yet.
CRA 2003; 104:1 Commission Directive to annex guidance.
CRA 2003; 110:1 EU releases final versions of five Detailed Guidance documents.
CRA 2003; 111:1 New SOPs required in order to comply with EU Detailed Guidance.
CRA 2003; 111:2 The Eudract database - a European register of clinical trials.
CRA 2003; 111:4 Application for Clinical Trial Authorisation.
CRA 2003; 111:6 Final Detailed Guidance on applications to Ethics Committees.
CRA 2003; 111:9 New guidance on safety reporting.
CRA 2003; 111:11 The European database of suspected unexpected serious adverse reactions (Eudravigilance).
CRA 2003; 114:8 Commission Directive latest.
   
2002  
CRA 2002; 82:8 More on EU GCP Directive guidelines.
CRA 2002; 87:1 GCP Directive Guidelines on track for June.
CRA 2002; 89:66 First detailed guidelines to support 2001/20/EC Directive now publicly available.
CRA 2002; 92:1 First Detailed Guidances to support implementation of GCP Directive released.
CRA 2002; 92:2 Draft guidance on the Trial Master File and archiving.
CRA 2002; 92:4 Guidelines on the qualifications of GCP inspectors.
CRA 2002; 92:5 Procedures for the verification of GCP compliance.
CRA 2002; 93:1 New detailed guidelines from EC.
CRA 2002; 94:1 EU Detailed Guidances now publicly available.
CRA 2002; 94:1 New guidance on the principles of GCP in the conduct in the European clinical trials.
CRA 2002; 94:2 Guidance for Ethics Committee applications.
CRA 2002; 94:5 The EUDRACT clinical trials database.
CRA 2002; 94:6 Detailed guidance on pre-trial authorisation.
CRA 2002; 94:7 Safety reporting and the SUSARs database.
CRA 2002; 96:1 EU Detailed Guidances subject to criticism.
CRA 2002; 97:1 Draft Detailed Guidance criticised.
CRA 2002; 97:1 Detailed Guidance requirements could force EU-destined research elsewhere.
CRA 2002; 97:2 Application for Ethics Committee opinion.
CRA 2002; 97:3 The EUDRACT trials database.
CRA 2002; 97:4 Clinical trial authorisation.
CRA 2002; 97:5 Adhere to ICH GCP and make it plain!
CRA 2002; 97:5 Safety reporting requirements: complications foreseen.
CRA 2002; 97:7 Three documents with the same reference number!
CRA 2002; 98:1 Serious reservations over EUDRACT.
CRA 2002; 99:8 New regulatory documents.
CRA 2002; 100:4 Current status of key European clinical research guidelines.
   
2001  
CRA 2001; 77:1 GCP Directive guidance awaited.
CRA 2001; 80:1 EU 'GCP Directive' - first draft guidance released for private consultation.

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