A newsletter for those involved in clinical trials. Published 20 times a year by Canary Ltd

Informed consent

The following articles on this topic have been published in CRAdvisor (CRA) – the year, issue number and starting page number for each are listed below:

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2007  
CRA 2007; 183:1 UK Clinical Trials Regulations amended for emergency research.
CRA 2007; 184:8 Consent in emergency research.
CRA 2007; 185:6 Guidance on consent and information sheets.
CRA 2007; 193:2 ABPI issues guidelines on secondary use of data for research.
   
2006  
CRA 2006; 166:5 Warning letters pick up more consent violations.
CRA 2006; 167:2 Standard clauses for data transfer are underused says EC report.
CRA 2006; 167:5 Do subjects really understand consent forms?
CRA 2006; 167:8 Model wording for consent forms.
CRA 2006; 169:2 EC issues revised Detailed Guidance on ethics committee applications.
CRA 2006; 170:6 Focusing on the subject in informed consent.
CRA 2006; 171:5 IRBs violate FDA regulations.
CRA 2006; 171:8 Parents and paediatric research.
CRA 2006; 172:3 FDA uncovers violations of regulations: consent deficiencies predominate.
CRA 2006; 172:8 FDA enforcement discretion.
CRA 2006; 179:5 A positive approach to paediatric informed consent.
CRA 2006; 180:4 CDRH inspections lead to new investigator warning letters.
CRA 2006; 181:8 Consent in emergency research.
   
2005  
CRA 2005; 146:7 Readability of trial documents.
CRA 2005; 148:3 Violation of consent puts patients at risk.
CRA 2005; 148:4 Amendment to UK trials legislation to enable studies in emergency medicine.
CRA 2005; 150:6 Investigator fails to impress inspectors.
CRA 2005; 152:5 Warning letter criticises consent documents.
CRA 2005; 155:2 Inspection reveals trial commenced without IND.
CRA 2005; 156:1 UK proposes amendment to clinical trials regulations.
CRA 2005; 160:4 Identifying the most frequent violations of FDA regulations.
CRA 2005; 161:6 CDRH issues more investigator warning letters.
   
2004  
CRA 2004; 132:3 Lessons to learn as jury clears cancer centre.
CRA 2004; 133:1 What is the impact of EU Directive 2001/20/EC on clinical research?
   
2003  
CRA 2003; 109:2 UK Department of Health seeks comments on procedures for informed consent.
CRA 2003; 112:7 Can technology enhance the consent process?
CRA 2003; 113:8 UK plans for legal representative.
CRA 2003; 114:1 UK publishes draft proposals on consent from legal representatives.
   
2002  
CRA 2002; 84:1 Warning of increase in law suits from subjects.
CRA 2002; 86:2 Consent by legally authorised representative must be lawful.
CRA 2002; 86:2 ICH GCP has improved trial quality in Europe - but safety reporting in the US is a cause for concern.
CRA 2002; 94:2 Guidance for Ethics Committee applications.
CRA 2002; 95:1 Call for amendment of Directive 2001/20/EC over emergency research.
CRA 2002; 98:1 Cancer centre damages.
   
2001  
CRA 2001; 65:4 Directive makes consent an important process.
CRA 2001; 66:5 Do consenting subjects really understand?
CRA 2001; 67:6 Consent forms and financial disclosure.
   
2000  
CRA 2000; 41:5 US guidance for research in mental disorders.
CRA 2000; 47:1 Guidelines for academic trials?
CRA 2000; 50:1 New Scottish Law on adults with incapacity.
   
1999  
CRA 1999; 19:4 US moves towards a consent form template.
CRA 1999; 20:1 Six-day consent rule is obligatory in Ireland.
CRA 1999; 20:1 Do your informed consent forms pass the NCI test?
CRA 1999; 24:3 Informed consent defined.
CRA 1999; 24:4 Consent elements tightened up in amended Directive?
CRA 1999; 24:5 Member States must define protection for vulnerable subjects.
CRA 1999; 26:4 Written informed consent now required in Japan.
CRA 1999; 27:3 Guidelines for researchers – patient information sheet and consent form.
CRA 1999; 29:4 Declaration of Ottawa protects children.
CRA 1999; 30:5 Additional requirements for informed consent.
CRA 1999; 31:6 Six-day consent rule in Ireland.
CRA 1999; 34:1 Consent forms forged?
   
1998  
CRA 1998; 3:3 Is delegation of consent acceptable?
CRA 1998; 6:2 Guidance on patient information and consent forms.
CRA 1998; 6:5 Protecting women in trials.
CRA 1998; 18:4 Detecting consent problems in the Slovak Republic.

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