A newsletter for those involved in clinical trials. Published 20 times a year by Canary Ltd

Children/paediatrics

The following articles on this topic have been published in CRAdvisor (CRA) – the year, issue number and starting page number for each are listed below:

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2007  
CRA 2007; 183:1 Peadiatric Regulation adopted.
CRA 2007; 184:2 EU Paediatric Regulation 1901/2006 now in force.
CRA 2007; 187:2 European Commission issues guidelines for paediatric investigation plans.
CRA 2007; 187:8 Initiative to reduce development costs.
CRA 2007; 190:8 Paediatric study costs on the up.
CRA 2007; 193:6 EMEA guideline on trials in small populations.
CRA 2007; 194:8 Templates for the EU Paediatric Regulation.
CRA 2007; 195:8 EMEA Paediatric Working Party meets for last time.
   
2006  
CRA 2006; 163:1 EC adopts modified proposal for a regulation on medicines for children.
CRA 2006; 164:2 Modifications to proposed EC paediatric regulations.
CRA 2006; 169:8 Common position reached on the paediatric regulation.
CRA 2006; 171:8 Parents and paediatric research.
CRA 2006; 173:2 FDA issues draft guidance on US trials involving children as subjects.
CRA 2006; 176:12 EMEA final guideline on pharmacovigilance in children.
CRA 2006; 177:6 EMEA finalises guideline on pharmacovigilance for medicines used by children.
CRA 2006; 179:1 Implementation of the Paediatric Regulation.
CRA 2006; 179:2 New guideline on the ethics of clinical trials in children.
CRA 2006; 179:5 A positive approach to paediatric informed consent.
CRA 2006; 182:2 Revised ethics guidance for trials in children.
   
2005  
CRA 2005; 143:1 Increase in paediatric research in USA and Europe predicted for 2005.
CRA 2005; 143:3 Conference on children's medicines.
CRA 2005; 154:4 EC consultation on regulation of paediatric medicines.
CRA 2005; 156:3 Centre accused of violating children's rights in AIDS research trials.
CRA 2005; 156:4 Special HHS protections for children in research.
CRA 2005; 157:6 EMEA drafts guideline for pharmacovigilance in children.
CRA 2005; 158:1 EMEA consults on draft guideline for pharmacovigilance in children.
CRA 2005; 158:8 Paediatric research.
CRA 2005; 159:1 Industry concerns over EMEA proposals for paediatric medicines regulation.
CRA 2005; 159:2 FDA issues draft guidance on complying with the Pediatric Research Equity Act.
CRA 2005; 161:2 Conflicts of interest for National Cancer Institute Pediatric Central IRB members.
CRA 2005; 162:4 Report from EFGCP Working Party on children's medicines.
CRA 2005; 162:8 Help for studies in children.
   
2004  
CRA 2004; 128:6 Draft EU regulation on medicinal products for paediatric use.
CRA 2004; 129:3 EC proposes regulation to increase products approved for paediatric use.
CRA 2004; 129:4 Commission proposal on medicines for paediatric use: rationale and overview.
CRA 2004; 130:6 FDA supports more access to information.
CRA 2004; 132:3 Paediatric trials on the way.
CRA 2004; 140:2 EC proposes regulation on paediatric medicines.
CRA 2004; 141:1 EU regulation proposed for promoting medicines for children.
CRA 2004; 141:7 Parental willingness in paediatric recruitment.
   
2003  
CRA 2003: 102:2 Mandatory paediatric testing in the USA?
CRA 2003; 102:6 New combination vaccine protects against five childhood diseases.
CRA 2003: 103:5 Paediatric clinical trials present new challenges.
CRA 2003; 110:5 EMEA focuses on extremes of age.
CRA 2003; 112:6 What motivates subjects to enter paediatric trials?
CRA 2003; 114:6 FDA discusses paediatric drug safety under Best Pharmaceuticals for Children Act.
CRA 2003; 114:7 Paediatric expert to sit on CDRH panel.
CRA 2003; 116:6 FDA draft guidance on pre-market assessment of paediatric medical devices.
CRA 2003; 116:7 Pediatric Research Equity Act approved.
CRA 2003; 116:8 FDA presents paediatric drug safety report.
CRA 2003; 117:6 US Senate approves Pediatric Rule.
CRA 2003; 122:7 Will you help seriously ill children to enjoy their last few months?
   
2002  
CRA 2002; 86:6 Better medicines for children.
CRA 2002; 89:1 HHS will enforce 'drugs for children' rule.
CRA 2002; 89:2 EU propose legalisation of obligatory paediatric trials.
CRA 2002; 99:7 Paediatric protection under scrutiny.
CRA 2002; 100:12 Overview of documents produced by the ICH process.
CRA 2002; 101:6 Design of orphan drugs trials in children.
   
2001  
CRA 2001; 60:6 Latest on paediatric studies.
CRA 2001; 63:1 Horrific extent of organ research revealed.
CRA 2001; 66:4 Guidance for paediatric trials.
CRA 2001; 69:1 FDA releases interim rule for paediatric trials.
CRA 2001; 72:2 New requirements for IRB review of paediatric trials.
CRA 2001; 74:6 FDA urged to waive parental consent for minors.
CRA 2001; 76:6 A European conference on clinical research in children.
CRA 2001; 77:3 FDA Drug Centre establishes new office.
   
2000  
CRA 2000; 40:6 Doctor forced to take child organs!
CRA 2000; 59:6 Paediatric trials are to be encouraged in the EU.
   
1999  
CRA 1999; 29:4 Declaration of Ottawa protects children.
CRA 1999; 31:4 Patient information sheets for children.
CRA 1999; 34:6 ADR reporting in children.
CRA 1999; 39:3 New guidelines for studies in children.

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